Cilastatin molecular weight
WebName: Cilastatin CAS#: 82009-34-5 (free acid) Chemical Formula: C16H26N2O5S Exact Mass: 358.15624 Molecular Weight: 358.45 Elemental Analysis: C, 53.61; H, 7.31; N, 7.82; O, 22.32; S, 8.95 Price and Availability Technical data Biological activity Solubility and formulation Protocols Calculators References WebOct 6, 2024 · It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of 380.43. It is very soluble in water and in methanol. Its empirical formula is C 16 H 25 N 2 O 5 SNa, and its structural formula is: Imipenem and Cilastatin for Injection, USP (I.V.) is buffered to provide solutions in the pH range of 6.5 to 8.5.
Cilastatin molecular weight
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WebAug 3, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, ... Cilastatin sodium was given intravenously to rabbits at doses up to 300 mg/kg/day and to rats subcutaneously at … WebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, respectively, approximately 3.2 and 1.9 times the RHD (based on body surface area). ... It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of …
WebMolecular Formula C13H20ClNO3 Molecular Weight 273.76 Catalogue Number AR-C02770 Parent Drug CILASTATIN CAS Number 877674-77-6 Cilastatin Ammonium Salt Synonym ammonium (Z)-7-(((R)-2-amino-2-carboxyethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoate Molecular Formula C16H25N2O5S . … WebIt is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, and its structural formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid.
WebCombination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. ... Molecular Formula. C12-H17-N3-O4-S.C16-H26-N2-O5-S. Molecular Weight. 657.8057 ... WebShowing 1-6 of 6 results for "cilastatin" within Products. Products Genes Papers Technical Documents Site Content Chromatograms. Filter & Sort. All Photos (1) Cilastatin sodium salt. ... Molecular Weight: 358.45. Compare Product No. Description SDS Pricing; SML1283: 50 mg/mL in DMSO/H 2 O, 1:1: Expand. Hide.
WebJan 10, 2024 · MOLECULAR FORMULA : C16-H26-N2-O5-S MOLECULAR WEIGHT : 358.50 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - …
WebMay 1, 2024 · Imipenem/cilastatin was administered intravenously to mice at doses up to 320 mg/kg/day (GD 6 to 15). In two separate studies, imipenem/cilastatin was administered to rats (GD 6 to 17 and GD 15 to … ebay bluetooth speakers usedWebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, … company revenue lookup ukWebCilastatin is excreted primarily in unchanged form in the urine, but about 12% of the drug appears as the metabolite N-acetylcilastatin [ 485 ]. In neonatal studies, the intravenous … ebay blush dressesWebA method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by … company revere containers 1974WebCilastatin UNII 141A6AMN38 Molecular formula C 16 H 26 N 2 O 5 S Molecular weight 358.45 Percent composition C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.94% … company review cloud kinetics tech pte. ltdWebFigure 1: Imipenem molecular structure (molecular weight = 299.347 grams/mole). Figure 2: Cilastatin molecular structure (molecular weight = 358.454 grams/mole). Meropenem Meropenem is a derivative of thienamycin. It does not require co-administration with cilastatin because it is not sensitive to renal dipeptidase. ebay blurex long range wirelessWebwhite, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is … company review cards