Fosphenytoin (Cerebyx) is a more water-soluble prodrug form of phenytoin that allows for faster IV infusion and less risk of extravasation injury. Because its molecular weight is different than that of phenytoin, one milligram of fosphenytoin does not equal one milligram of phenytoin. To avoid confusion, … See more The basis of loading dose calculations involves a drug's volume of distribution (Vd). For phenytoin, a Vdof 0.7 L/kg is used. The following equation is a simple pharmacokinetic … See more There is limited data regarding an adjustment factor for loading phenytoin in obese patients. The most commonly cited trial5only included 14 obese patients, of which had a mean weight 78% above ideal body weight. Based … See more In patients with hypoalbuminemia, a corrected equation must be used to account for reduced phenytoin protein binding. This calculator uses the average of the following … See more Phenytoin oral loading doses may be advantageous in stable patients with subtherapeutic phenytoin concentrations, particularly in those presenting to the emergency department without IV access. Because phenytoin … See more WebFosphenytoin Chemical formula: C16H15N2O6P Drugbank ID: DB01320 ATC code: N03AB05 The information below refers to products available in the United States that contain fosphenytoin. Products containing fosphenytoin fosphenytoin systemic Brand names: Cerebyx, Sesquient Drug class: hydantoin anticonvulsants
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WebMay 20, 2024 · Maintenance Doses: Initial Maintenance Dose: 2 to 4 mg PE/kg/day IV administered 12 hours after loading dose; infuse at 1 to 2 mg PE/kg/min... Maintenance … scratch tablet
Dilution Cerebyx ® -fosphenytoin - GlobalRPH
WebFosphenytoin Load. Questions. 1.Desired Concentration? 2.Actual Concentration? 3.Weight? About. This formula calculates the fosphenytoin loading dose. Rapidly … WebFosphenytoin C16H15N2O6P CID 56339 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... WebSep 4, 2024 · Fosphenytoin is a medication used to manage seizures (treatment of generalized tonic-clonic status epilepticus, focal [partial] onset seizures, or generalized onset seizures, and for the prevention and treatment of seizures occurring during neurosurgery). It is a water-soluble phenytoin prodrug that can be employed in situations where phenytoin … scratch tables