WebMar 24, 2016 · A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis The safety and scientific validity of this study is the responsibility of the … WebMay 4, 2024 · In February, the first patient was dosed in the Phase 2 CITADEL-202 trial, studying the selective PI3Kδ inhibitor INCB50465 as monotherapy in patients with diffuse large B-cell lymphoma (DLBCL). In April, initial clinical data from INCB54828, Incyte’s selective FGFR1/2/3 inhibitor, was presented at the 2024 AACR meeting, including safety …

MPN-075 Efficacy and Safety of Add-on Parsaclisib to Ruxolitinib ...

WebOct 11, 2024 · Incyte’s lead drug, Jakafi (ruxolitinib), is a first-in-class JAK1/JAK2 inhibitor approved in the United States for the treatment of patients with polycythemia vera (“PV”), who have had an... Webatopic dermatitis, pemigatinib in bladder cancer and ruxolitinib with INCB50465 in refractory myelofibrosis; our plans and expectations for development of and clinical trials our other product candidates, including the potential timing for regulatory submissions; our expected year-end level of cash and marketable securities; cowan edmonton

Clinical Trials Register

WebMay 1, 2024 · INCB50465 (PI3Kδ) Follicular lymphoma Phase 2 (CITADEL-203) INCB50465 (PI3Kδ) Marginal zone lymphoma Phase 2 (CITADEL-204) INCB50465 (PI3Kδ) Mantle cell lymphoma ... WebSponsor Protocol Number: INCB50465-313: Start Date *: 2024-03-10: Sponsor Name: Incyte Corporation Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Combination of PI3Kδ Inhibitor Parsaclisib and Ruxolitinib in Participants With Myelofibrosis: Medical condition: myelofibrosis WebINCB050465 INCB 50465 INCB-50465 INCB50465 WHO 10589: PIK3CD inhibitor 26: Parsaclisib (INCB050465) inhibits PI3K-delta, blocking activation of AKT signaling pathway and leading to apoptosis of PIK3CD expressing tumor cells (PMID: 31749910). Pegfilgrastim Neulasta: GCSF-SD01 dishwasher rollers repair